Our Vita-Assay™ and Vita-Cap™ technologies, provide efficient enrichment of live rare cells from a standard tube of blood which can then be used for cellular and molecular analyses on genetics and physiological testing, and disease prediction.
Study on Mechanism of Metastasis: isolation and culture of metastasis-initiating cells.
Metastasis Models: development of metastatic cell line and mouse models.
Drug Discovery: single cell sorting for discovery of metastasis targets.
Mutation Analysis: cancer cell isolation and culture for cancer genomics DNA sequencing.
Molecular diagnostics for therapy guiding: Global gene expression profiling of CTCs and immune cells enriched by Vita-Cap™ can be developed for guiding therapy of individual patients.
Companion diagnostics in cardiovascular disease: Blood test based on circulating endothelial cells (CECs) for high risk of cardiovascular disease.
Genetic testing of fetal cells during pregnancy:Fetal cells in maternal uterus or blood enriched by Vita-Cap™tubes at point-of-care, followed by FACS, for performing genetic testing of fetal cells in pregnant women.
Development of drugs targeted to seprase and DPP4: Monoclonal antibodies against DPP4 and Peptide Inhibitors against seprase suppress tumor invasion, metastasis and angiogenesis.